Biosafety
According to the World Health Organization:
Biosafety is the safe working practices associated with handling of biological materials, particularly infectious agents. It addresses containment principles, technologies and practices that are implemented to prevent the unintentional exposure to pathogens and toxins, or their accidental release. Responsible laboratory practices, including protection, control and accountability for valuable biological materials will help prevent their unauthorized access, loss, theft, misuse, diversion or intentional release.
Biosafety is the safe working practices associated with handling of biological materials, particularly infectious agents. It addresses containment principles, technologies and practices that are implemented to prevent the unintentional exposure to pathogens and toxins, or their accidental release. Responsible laboratory practices, including protection, control and accountability for valuable biological materials will help prevent their unauthorized access, loss, theft, misuse, diversion or intentional release.
Classification of pathogenic biological agents by pathogenicity and degree of hazardousness
NB: These are not the same with the BSLs.
Pathogenicity group I is the most hazardous group, and pathogenicity group IV is the least hazardous group of biological agents.
Pathogenicity group I is the most hazardous group, and pathogenicity group IV is the least hazardous group of biological agents.
Pathogenicity Group I
Ex: Yersinia pestis
pathogenic biological agents that cause particularly dangerous infectious diseases of humans and (or) animals with a high mortality rate (lethality), easily spreading from an infected organism to a healthy one, as a rule, for which there are no vaccines and effective therapies
Pathogenicity Group II
Ex: Bacillus anthracis
pathogenic biological agents that cause infectious and (or) parasitic diseases of humans and (or) animals, easily spreading from an infected organism to a healthy one, for which effective means and methods of treatment and prevention, including vaccines, are available
Pathogenicity Group III
Ex: Shigella spp.
pathogenic biological agents causing infectious and (or) parasitic diseases of humans and (or) animals or capable of causing significant harm to plants, characterized by minimal spread from an infected organism to a healthy one, for which effective means and methods of treatment and prevention, including vaccines, are available
Pathogenicity Group IV
Ex: Escherichia coli
pathogenic biological agents causing infectious and (or) parasitic diseases of humans and (or) animals or capable of harming plants, as a rule, not spreading from an infected organism to a healthy one, for which effective means and methods of treatment and prevention, including vaccines, are available
Equipment
technical and personal protective equipment that keeps laboratory personnel & environment safe.
Biosafety cabinets
Biological safety cabinets (BSCs) are used to protect personnel, products and the environment from exposure to biohazards and cross contamination.
BSC classes
There are three classes of BSCs: Class I, II and III.
- Class I BSCs are suitable for work involving low to moderate-risk agents. Class I cabinets are used to enclose equipment (e.g., centrifuges, harvesting equipment or small fermenters) or procedures with potential to generate aerosols (e.g., cage dumping, tissue homogenization or culture aeration).
- Class II BSCs provide a partial barrier for the safe manipulation of low, moderate and high-risk microorganisms. Class II cabinets, which are the most frequently used in research and clinical laboratories, are divided into four types (Types A1, A2, B1 and B2).
- The Class III BSC is a totally enclosed, gas-tight ventilated cabinet, and provides the highest level of personnel, environmental and product protection.
Personal Protective Equipment
A Personal Protective Equipment (PPE) is clothing or equipment designed to reduce student/employee exposure to chemical, biological, physical or any other hazards during working or strudying processes.
It is used to protect students/employees when engineering and administrative controls are not feasible to reduce the risks to acceptable levels.
The 4 Basic Types of PPE:
1) Face and Eye Protection
2) Respiratory Protection
3) Skin and Body Protection
4) Hearing Protection.
It is used to protect students/employees when engineering and administrative controls are not feasible to reduce the risks to acceptable levels.
The 4 Basic Types of PPE:
1) Face and Eye Protection
2) Respiratory Protection
3) Skin and Body Protection
4) Hearing Protection.
Biosafety Levels
used to identify the protective measures needed in a laboratory setting to protect people and environment
Quick Learn Lesson
Recognizing the Biosafety Levelshttps://www.cdc.gov/training/quicklearns/biosafety/
Spills
is an unintended release of a potentially hazardous material
Biohazardous spill response
(for low risk spills)
(for low risk spills)
1
Alert
Alert your Professor, Superviser, etc.
2
Remove
Remove and disinfect any material that has been splashed on you and remove/disinfect contaminated clothing
3
Isolate
Secure the affected area and post biohazard-warning signs.
4
Spill Cleanup
- Cover the spill with paper towels or other absorbent material to absorb the spill and prevent further aerosolization.
- Pour disinfectant gently over the covered spill, working from the outside inwards.
- Wait at least 15 minutes for the disinfectant to penetrate through the contained spill and achieve the required contact time for disinfection.
- Using the appropriate tools (i.e., shovels, forceps), remove the absorbent material and place it in a biohazard bag for autoclaving and subsequent disposal.
- Repeat Spill Cleanup Procedure over the original spill area to ensure disinfection and cleanup.
5
Alert
Notify your supervisor and Environmental and Occupational Safety Department
Contacts
Address
53 Kabanbay Batyr Ave., Astana
Block 1, Room 1177A
53 Kabanbay Batyr Ave., Astana
Block 1, Room 1177A
Tilda Publishing
Phone
8(7172)70-6219
8(7172)70-6364
8(7172)70-6219
8(7172)70-6364
Email
osh@nu.edu.kz
hsetraining@nu.edu.kz
osh@nu.edu.kz
hsetraining@nu.edu.kz
Office visits
8:30am-5:30pm
Monday-Friday
8:30am-5:30pm
Monday-Friday
Tansholpan Yakhiyayeva – Senior Manager